Simon Arridge
University of College, London
Date: August 12, 2003
In the first part of this talk I will discuss methods for reconstruction of spatially-varying optical absorbtion and scattering images from measurement of transmitted light through highly scattering media. The problem is posed in terms of non-linear optimisation, based on a forward model of diffusive light propagation, and the principle method is linearisation using the adjoint field method. In the second part I will discuss the particular difficulties involved in imaing the brain. These include: - Accounting for non or weakly scattering regions that do not satisfy the diffusion approximation (the void problem) - Accounting for anisotropic scattering regions - Constructing realistic 3D models of the head shape - Dynamic imaging incorporating temporal regularisation.